New technologies are increasingly being implemented in people’s daily lives and with the growth of smart devices around the globe, the users’ needs and demands have changed in favor of more technological cities, cars, houses, and airplanes.Therefore, it is important to define the stakeholder’s needs and requirements to understand which techno

Abstract Environmental and physiological situations can challenge the balance between protein synthesis and folding capacity of the endoplasmic reticulum (ER) and cause ER stress, a potentially lethal condition.The unfolded protein response (UPR) restores ER homeostasis or actuates programmed cell death (PCD) when ER stress is unresolved.The cell f

While several papers have highlighted a lack of evidence to scale social innovations in health, fewer have explored decision-maker understandings of the relative merit of different types of evidence, how such data are interpreted and applied, and what practical support is required to improve evidence generation.The objectives of this paper are to u

Natural disasters are becoming increasingly regional, frequent, and complex.Semi-quantitative risk assessments based on risk indices or relative risk levels lack quantitative parameters to characterize losses adequately.This study focuses on earthquakes and geological disasters, quantitatively assessing the risk of Desk and Shelf probable maximum l